NP Thyroid is a natural preparation derived from porcine thyroid glands. The tablets contain both tetraiodothyronine sodium (T4 levothyroxine) and triiodothyronine sodium (T3 liothyronine) providing 38 mcg levothyroxine (T4) and 9 mcg liothyronine (T3) per grain of thyroid (or per 65 mg of the labeled amount of thyroid). The inactive ingredients are calcium stearate, dextrose monohydrate, maltodextrin, and mineral oil.

NP Thyroid tablets (USP) are indicated:

1. As replacement or supplemental therapy in patients with hypothyroidism of any type, except transient hypothyroidism during the recovery phase of subacute thyroiditis. This category includes cretinism, myxedema, and ordinary hypothyroidism in patients of any age (children, adults, the elderly), or state (including pregnancy); primary hypothyroidism resulting from functional deficiency, primary atrophy, partial, or total absence of thyroid gland, or the effects of surgery, radiation, or drugs, with or without the presence of goiter; and secondary (pituitary), or tertiary (hypothalamic) hypothyroidism.

2. As pituitary TSH suppressants, in the treatment or prevention of various types of euthyroid goiters, including thyroid nodules, subacute or chronic Iymphocytic thyroiditis (Hashimoto's), multinodular goiter, and in the management of thyroid cancer.

3. As diagnostic agents in suppression tests to differentiate suspected mild hyperthyroidism or thyroid gland autonomy.
NP Thyroid Approximate Equivalent Strength Chart
½ grain              30mg    
1 grain              60mg    
1 ½ grain              90mg    

Source: United States Pharmacopoeia
Drug Information 2000, 20th Edition.
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CONTRAINDICATIONS: Thyroid hormone preparations are generally contraindicated in patients with diagnosed but as yet uncorrected adrenal cortical insufficiency, untreated thyrotoxicosis, and apparent hypersensitivity to any of their active or extraneous constituents. There is no well-documented evidence, however, of true allergic or idiosyncratic reactions to thyroid hormone.


SIDE EFFECTS: Adverse reactions other than those indicative of hyperthyroidism because of therapeutic overdosage, either initially or during the maintenance period, are rare. If you experience chest pain, increased pulse rate, palpitations, excessive sweating, heat intolerance, nervousness, or any other unusual event, contact your physician immediately.


Any reference to "brand comparison" or other comparative or "generic" language appearing in this communication and/or any attachment hereto is not an assertion of therapeutic equivalency, but in fact means the following: Based on active ingredients, Acella's product competes with the designated brand names and NDC numbers stated; provided, however, that: (1) all prescription substitutions and/or recommendations using Acella's product shall be made subject to state and federal statutes as applicable; (2) Acella's product is not an Orange Book product; and (3) Acella's product has not been subjected to FDA therapeutic equivalency or other equivalency testing.
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