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Did you know?
Up to

of patients may
continue to have symptoms
despite normal TSH level1
A study showed a significantly
greater percentage of people being treated for hypothyroidism preferred a natural* desiccated thyroid (NDT, or sometimes called DTE) treatment to one with a synthetic hormone alone2
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What is NP Thyroid®?

NP Thyroid® is a natural* desiccated thyroid therapy option that can help you individualize
your approach to treating your hypothyroidism.

Why NP Thyroid®?
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Naturally* derived therapy containing T4 and T3 in one pill3

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Dye-free and contains no ingredient made from a gluten-containing grain (wheat, barley, or rye)3

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Available in 5 dose strengths for easy titration to achieve the necessary therapeutic range3

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Works within 2 to 3 weeks3

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Only 3 inactive ingredients3

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Uncoated tablet for oral administration3

Produced to the highest standards
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Batch-to-batch tested to ensure every dose delivers consistent T4 and T34
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Naturally* derived thyroid extract is processed in an FDA-regulated facility4
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Made with the highest quality standards under current Good Manufacturing Practice (cGMP) regulations4
What does NP Thyroid® treat?

NP Thyroid® is used as a replacement or supplemental therapy in patients with
hypothyroidism of various causes, including:

  • Congenital hypothyroidism
  • Myxedema
  • Hypothyroidism in patients of any age (children, adults, the elderly) or state (including pregnancy)
  • Primary hypothyroidism resulting from functional deficiency
  • Primary atrophy
  • Partial or total absence of the thyroid gland
  • The effects of surgery, radiation, or drugs with or without the presence of goiter
  • Secondary (pituitary) or tertiary (hypothalamic) hypothyroidism
  • May be used as a TSH suppressant, in the treatment or prevention of various types of euthyroid goiters, including thyroid nodules, subacute or chronic lymphocytic thyroiditis (Hashimoto’s), multinodular goiter, and in the management of thyroid cancer
Dosage and how to take NP Thyroid®3
Available in the following dosage levels7:
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The dosage of thyroid hormones is specific to each individual and must be individualized according to licensed prescriber, patient responses, and laboratory findings.
  • Available in multiple strengths for easy titration to achieve the necessary therapeutic range
  • Adequate therapy usually results in normal TSH and T4 levels after 2 to 3 weeks of therapy
  • Readjustments of thyroid hormone dosage should be made within the first 4 weeks of therapy, after clinical and laboratory evaluations by your healthcare provider
It is important to take NP Thyroid® exactly as your healthcare
provider prescribed to help you manage your hypothyroidism.
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Take NP Thyroid® once a day, at the same time, with an 8 oz glass of water.5,6
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Take NP Thyroid® on an empty stomach, at least 30 to 60 minutes before consuming any food or caffeine. This means no eating or drinking anything other than water! Fasting increases absorption.7
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If you’ve already eaten, NP Thyroid® can be taken two hours after consumption with an 8 oz glass of water, again waiting 30-60 minutes before consuming food or caffeine.7
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Take NP Thyroid® 4 hours before or after taking iron, calcium supplements, antacids, cholestyramine.7
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Soy, cottonseed meal, walnuts, fiber, and grapefruit juice can affect the absorption of NP Thyroid®. If you eat any of these on a regular basis, tell your doctor, as your dose may need to be adjusted.8,9
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Get NP Thyroid®
Use the tools below to help you find a physician that you may speak with regarding NP Thyroid®, or use the pharmacy finder tool to locate a pharmacy from which you may purchase NP Thyroid®.
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Find a healthcare provider
Find healthcare providers in your area that may be able to assist you.
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Find a pharmacy
Find pharmacies in your area where you can find NP Thyroid®.
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Sign up to download a helpful patient brochure that answers common questions about hypothyroidism and NP Thyroid®.

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Get advice from the experts
Get advice, tips, and information on living with hypothyroidism from our expert bloggers. Topics include nutrition, exercise, well-being advice, and more.
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Find more resources
Visit the resources page for more help in the form of FAQs, checklists, app downloads, and other information.
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*Naturally derived refers to the biological nature of the porcine-derived desiccated thyroid ingredient found in the product.

Important Risk Information

Drugs with thyroid hormone activity, alone or together with other therapeutic agents, have been used for the treatment of obesity. In euthyroid patients, doses within the range of daily hormonal requirements are ineffective for weight reduction. Larger doses may produce serious or even life-threatening manifestations of toxicity, particularly when given in association with sympathomimetic amines such as those used for their anorectic effects.
  • NP Thyroid® is contraindicated in patients with uncorrected adrenal insufficiency, untreated thyrotoxicosis, and hypersensitivity to any component of the product.
  • In the elderly and in patients with cardiovascular disease, NP Thyroid® should be used with greater caution than younger patients or those without cardiovascular disease.
  • Use of NP Thyroid® in patients with diabetes mellitus or adrenal cortical insufficiency may worsen the intensity of their symptoms.
  • The therapy of myxedema coma requires simultaneous administration of glucocorticoids.
  • Concomitant use of NP Thyroid® with oral anticoagulants alters the sensitivity of oral anticoagulants. Prothrombin time should be closely monitored in thyroid-treated patients on oral anticoagulants.
  • In infants, excessive doses of NP Thyroid® may produce craniosynostosis.
  • Partial loss of hair may be experienced by children in the first few months of therapy but is usually transient.
  • Adverse reactions associated with NP Thyroid® therapy are primarily those of hyperthyroidism due to therapeutic overdosage.
  • Many drugs and some laboratory tests may alter the therapeutic response to NP Thyroid®. In addition, thyroid hormones and thyroid status have varied effects on the pharmacokinetics and actions of other drugs. Administer at least 4 hours before or after drugs that are known to interfere with absorption. Evaluate the need for dose adjustments when regularly administering within one hour of certain foods that may affect absorption.
  • NP Thyroid® should not be discontinued during pregnancy, and hypothyroidism diagnosed during pregnancy should be promptly treated.


NP Thyroid® (thyroid tablets, USP) is a prescription medicine that is used to treat a condition called hypothyroidism from any cause, except for cases of temporary hypothyroidism, which is usually associated with an inflammation of the thyroid (thyroiditis). It is meant to replace or supplement a hormone that is usually made by your thyroid gland.

NP Thyroid® is also used in the treatment and prevention of normal functioning thyroid goiters, such as thyroid nodules, Hashimoto’s thyroiditis, multinodular goiter, and in the management of thyroid cancer.